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We Have One Mission
End ALS.
We are the world's most comprehensive drug discovery lab focused solely on ALS.
As a nonprofit, our cutting-edge research is funded
by a global community united in ending ALS.
Without research there are no treatments.
Learn Why We're Leaders In Als Research
Can We Help You Find What You Need?
This is Your Lab
As you read this, our team of researchers and scientists are urgently working in our Boston-area lab – screening drugs, studying animal models, and collecting and analyzing data from people with ALS. ALS is complex, and the science is complicated, but we are relentless. We will not stop until we have treatments for everyone living with ALS.
“I support ALS TDI because not only is their focus on ALS research and finding a treatment, but ALS TDI focuses on the ALS community, those actually living with the disease. ALS TDI understands the urgency that people with ALS live with in finding a treatment and is driven by that urgency.”
Jenny Dwyer, Member of the Board of ALS TDI
- Jenny Dwyer, Member of the Board of ALS TDI, wife of Pat Dwyer, diagnosed with ALS in 2005 and passed away in 2013
“ALS TDI is one of the world's most transformative medical research institutes focused on ALS. We have applied business principles with the leadership of Dr. Steve Perrin to find a cure for ALS! I am proud to lead that effort as its Chairman.”
Augie Nieto, Chairman of the Board of ALS TDI
- Augie Nieto, Chairman of the Board of ALS TDI, living with ALS since 2005

Latest ALS Research News
Tuesday, June 22, 2021
Dr. Kyle Denton: Introducing the Newest Member of ALS TDI’s Leadership Team
Monday, June 7, 2021
ALS TDI: A Drug Discovery “Engine,” Helping Treatments Get to Trials
Monday, April 26, 2021
ALS TDI Joins Forces with Duke ALS Clinic Researchers to Study Rare ALS Reversals
Tuesday, April 6, 2021
Induced Pluripotent Stem Cells at ALS TDI
More ALS Research News
Relentless Research

Relentless Research

At the ALS Therapy Development Institute (ALS TDI) our sole mission is to discover and develop treatments for amyotrophic lateral sclerosis (ALS) as quickly as possible. ALS TDI is the most comprehensive drug discovery lab dedicated to ALS research. As one of the world's only nonprofit biotech companies, we are led by drug development experts and people with ALS.
ALS Research
Fueled By the Community

Fueled By the Community

As a nonprofit, we are only answerable to our supporters, the ALS community. Our research is funded by the ALS community, a global network of supporters whose lives have been affected by this disease, and who are unified to end ALS. We're getting closer, but we need your help.
Help Fund Treatments
Making An Impact

Making An Impact

Our science team invented AT-1501, a promising treatment for ALS that is currently in trials. We also innovated the first ALS Precision Medicine Program to discover more potential treatments faster. Our team is working urgently to identify more potential treatments and have them made available for people with ALS.
About Our Work

News & Events

Raising ALS Awareness Around the World on International ALS/MND Day
More ALS TDI News
Dr. Kyle Denton: Introducing the Newest Member of ALS TDI’s Leadership Team
More Research News
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